Friday, November 8, 2013

Journal club: One happy epigenetic family

This week's journal club paper: A SWI/SNF Chromatin-Remodeling Complex Acts in Noncoding RNA-Mediated Transcriptional Silencing by Zhu et al. (2013).

This paper was great.

My comment:
"I thought this paper was excellent. It painted a great story showing that the three major elements typically implicated in epigenetic regulation are elements of the same pathway. I don't think they made a very strong case that this regulatory pathway is important for elements other than transposons and repeats, but seeing as how transposons are such a large component of genomes, I think this work is important. This was good stuff."

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